This is Starwest's nitrogen-flushed double wall silverfoil pack. Used as an infusion, decoction, extract, tincture and poultice. Used throughout the Indian subcontinent as a poultice for skin diseases and the healing of wounds. It also has an ancient reputation for aiding mental clarity and lowering blood pressure. Hydrocotyle asiatica, listed by Grieve and King's, is sometimes listed as a synonym, but Oriental medical references say that Hydrocotyle is actually a different and medicinally inferior plant. Centella's saponins (including asiaticoside, madecassoside and madasiatic acid) seem to reduce scar formation in wound healing by inhibiting the production of connective tissue as they simultaneously close the wound. As the research below indicates, Centella has been experimentally shown to be 'effective in venous insufficiency, reducing ankle edema, foot swelling, capillary filtration rate and improving microcirculatory parameters.' The herb is very good news for varicose veins. This demonstrable improvement in microcirculatory efficiency may explain Gotu Kola's ancient reputation as an aid to mental clarity, high blood pressure, fever, rheumatism and mental disorders. http://www.herbmed.org/Herbs/Herb95.htm: Clinical Trials Microcirculatory parameters improved for 87 patients with chronic venous hypertensive microangiopathy taking 30 mg bid or 60 mg bid for 2 months Cesarone 1994 Bioavailability for asiatic acid and asiaticoside was quite similar, about 600 ng.h/ml, in 12 healthy Rush 1993 Review finds that Centella asiatica is effective in venous insufficiency, reducing ankle edema, foot swelling, capillary filtration rate and improving microcirculatory parameters Cesarone 1992 High circulating endothelial cells in postphlebitic patients was brought down by C asiatica triterpenic fraction Montecchio 1991 Varicose vein patients taking 60 mg/day for three months had declines in serum uronic acid 467 to 231 mcg/ml, beta-glycuronidase 1.8 to 1.2 microM, acetylglucosaminidase 23 to 18, arysulfatase 78 to 42 nM Arpaia 1990 Four weeks of triterpene fraction decreased capillary filtration rate, ankle circumference and edema in patients with venous pressure greater than 42 mmH Belcaro 1990 Two weeks' treatment with total triterpenic fraction, 60 mg, tid, decreased wheal disappearance time, indicating decreased capillary filtration and permeability Belcaro 1990 Plasma levels in humans, measured by HPLC, are higher with continuing twice daily ingestion than single dose of 30 or 60 mg of triterpenic fraction of Centella Grimaldi 1990 Titrated extract reduced symptoms of heaviness in the lower limbs and edema and improved venous distensibility in a double-blind randomized trial with 94 patients with venous insufficiency Pointel 1987 Observational Studies/Case Reports Scleroderma patients benefited from madecassol, which contains asiaticoside [Article in Russian] Guseva 1998 Iron absorption i

This is a potent 5 to 1 powdered extract, meaning that one gram of extract is equal in potency to 5 grams of herb. This extract is packed in Plum Flower Brand's nitrogen-flushed, safety-sealed dispenser bottle, a sample of which is pictured above. Plum Flower is one of the most distinguished herb houses in the world. This is a pure herbal product with no additives. Extracted from sulfur-free and chlorine-free herbs for superior quality. Manufactured in a low-temperature water extraction process to preserve herb integrity. Extracted essential oils are replenished for proper potency. Strict quality control testing to ensure microbiological and heavy metal safety. Only powdered herb added to maintain purity (no artificial fillers such as lactose, cellulose or starch used). TLC (Thin-layer Chromatography) tested to guarantee product quality. Plum Flower takes great care to preserve delicate herbal oils, which are first evaporated using either a water or water-alcohol base in a process that never exceeds 100° centigrade. Sealed vacuum chargers precisely control the temperature, ensuring that none of the oils are lost. Cheaper, high-temperature methods are common industry practice, but these tend to burn off the vital oils. The facilities in Lanzhou and Guang Zhou, China, scientifically test each batch of herbs before, during and after the processing to make sure that all the active ingredients are present. Herbs are also tested to ensure that the formulas surpass all FDA guidelines regarding heavy metals. Those herbs exported to the U.S. are voluntarily submitted to the FDA for approval. Finally, batches are regularly sent out for quality control testing in third-party labs to double-ensure that Plum Flower products are 100% free of pharmaceuticals, preservatives and dyes. The Lanzhou and Guang Zhou factories are so clean, they are certified by the Australian Governments Therapeutic Goods Administration (GMP). These standards surpass any of the FDA, and are considered the highest for any government agency in the world. Varuna Fulfillment Center items are special ordered. These take an extra week to deliver.

Gotu Kola is known in India and Pakistan as a 'longevity' herb, though this has not been proven. It is used to increase energy, improve memory, and alleviate depression. Some people are using to treat Alzheimer's disease. It is also used externally on wounds, burns, and psoriasis. It seems to strengthen the walls of blood vessels, thus making it a possible treatment for varicose veins. Grieve's classic 'A Modern Herbal': 'A valuable medicine for its diuretic properties; has long been used in India as an aperient or alterative tonic, useful in fever and bowel complaints and a noted remedy for leprosy, rheumatism and ichthyosis; employed as a poultice for syphilitic ulcers. In small doses it acts as a stimulant, in large doses as a narcotic...'

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This is Frontier's nitrogen-flushed double wall silverfoil pack. Some Frontier packs are double wall wax-lined paper. Used as an infusion, decoction, extract, tincture and poultice. Used throughout the Indian subcontinent as a poultice for skin diseases and the healing of wounds. It also has an ancient reputation for aiding mental clarity and lowering blood pressure. Hydrocotyle asiatica, listed by Grieve and King's, is sometimes listed as a synonym, but Oriental medical references say that Hydrocotyle is actually a different and medicinally inferior plant. Centella's saponins (including asiaticoside, madecassoside and madasiatic acid) seem to reduce scar formation in wound healing by inhibiting the production of connective tissue as they simultaneously close the wound. As the research below indicates, Centella has been experimentally shown to be 'effective in venous insufficiency, reducing ankle edema, foot swelling, capillary filtration rate and improving microcirculatory parameters.' The herb is very good news for varicose veins. This demonstrable improvement in microcirculatory efficiency may explain Gotu Kola's ancient reputation as an aid to mental clarity, high blood pressure, fever, rheumatism and mental disorders. http://www.herbmed.org/Herbs/Herb95.htm: Clinical Trials Microcirculatory parameters improved for 87 patients with chronic venous hypertensive microangiopathy taking 30 mg bid or 60 mg bid for 2 months Cesarone 1994 Bioavailability for asiatic acid and asiaticoside was quite similar, about 600 ng.h/ml, in 12 healthy Rush 1993 Review finds that Centella asiatica is effective in venous insufficiency, reducing ankle edema, foot swelling, capillary filtration rate and improving microcirculatory parameters Cesarone 1992 High circulating endothelial cells in postphlebitic patients was brought down by C asiatica triterpenic fraction Montecchio 1991 Varicose vein patients taking 60 mg/day for three months had declines in serum uronic acid 467 to 231 mcg/ml, beta-glycuronidase 1.8 to 1.2 microM, acetylglucosaminidase 23 to 18, arysulfatase 78 to 42 nM Arpaia 1990 Four weeks of triterpene fraction decreased capillary filtration rate, ankle circumference and edema in patients with venous pressure greater than 42 mmH Belcaro 1990 Two weeks' treatment with total triterpenic fraction, 60 mg, tid, decreased wheal disappearance time, indicating decreased capillary filtration and permeability Belcaro 1990 Plasma levels in humans, measured by HPLC, are higher with continuing twice daily ingestion than single dose of 30 or 60 mg of triterpenic fraction of Centella Grimaldi 1990 Titrated extract reduced symptoms of heaviness in the lower limbs and edema and improved venous distensibility in a double-blind randomized trial with 94 patients with venous insufficiency Pointel 1987 Observational Studies/Case Reports Scleroderma patients benefited from madecassol, which contains asiaticoside [Article in Russian] Guseva 1

Gotu Kola is known in India and Pakistan as a 'longevity' herb, though this has not been proven. It is used to increase energy, improve memory, and alleviate depression. Some people are using to treat Alzheimer's disease. It is also used externally on wounds, burns, and psoriasis. It seems to strengthen the walls of blood vessels, thus making it a possible treatment for varicose veins. Grieve's classic 'A Modern Herbal': 'A valuable medicine for its diuretic properties; has long been used in India as an aperient or alterative tonic, useful in fever and bowel complaints and a noted remedy for leprosy, rheumatism and ichthyosis; employed as a poultice for syphilitic ulcers. In small doses it acts as a stimulant, in large doses as a narcotic...'

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Gotu Kola is known in India and Pakistan as a 'longevity' herb, though this has not been proven. It is used to increase energy, improve memory, and alleviate depression. Some people are using to treat Alzheimer's disease. It is also used externally on wounds, burns, and psoriasis. It seems to strengthen the walls of blood vessels, thus making it a possible treatment for varicose veins. Grieve's classic 'A Modern Herbal': 'A valuable medicine for its diuretic properties; has long been used in India as an aperient or alterative tonic, useful in fever and bowel complaints and a noted remedy for leprosy, rheumatism and ichthyosis; employed as a poultice for syphilitic ulcers. In small doses it acts as a stimulant, in large doses as a narcotic...'